Tickborne BBB Direct Detect 3 day – dPCR | Lyme & Co-Infections
$1,843.00
The next generation of Lyme + Co-Infection Diagnostics—designed to detect at every stage
The most sensitive test methodology available for direct detection of Bartonella, Babesia, and Borrelia species (spp). (BBB) infections.
People can be exposed to Bartonella, Babesia, and Borrelia through exposure to ticks, fleas, lice, sand flies, and potentially spiders. These vectors can carry multiple pathogens at once, making co-infections common. These stealth pathogens can cause overlapping, persistent symptoms that are often misdiagnosed. Identifying which of these pathogens are present helps providers tailor treatment more effectively—especially since each requires a different therapeutic approach. Without proper testing, co-infections can be missed, leading to incomplete or ineffective care.
Discover the Power of MosaicDX’s Lyme Borrelia Direct Detect profile
Direct testing is particularly valuable in detecting the current presence of pathogens when antibody responses might be absent or unclear. Many patients with detectable spp. DNA never develop detectable antibodies, while others may only show very low titers. The result is that many patients with active pathogens are missed by both conventional PCR and antibody testing. Traditional testing methods may miss active infections due to low pathogen levels or antibody variability.
- Identifies a broad range of Bartonella, Babesia and Borrelia species – utilizing genus level primers
- Identifies cases missed by antibody testing by utilizing direct multiplex DNA detection
- Detects at lower levels by enriching whole blood to increase DNA detection capabilities for Bartonella infections
- Increased sensitivity up to10 times more patients are identified positive when compared to conventional detection methods like qPCR, NGS, and other direct detection methods.
- Confirms DNA in blood for a broad range of Bartonella, Borrelia, and Babesia – Ensures that infection with less common species is not missed.
Tickborne BBB Direct Detect dPCR, confirms current presence of pathogens by directly detecting genus-level DNA for a broad range of Bartonella, Borrelia, and Babesia species (spp) in whole blood. This approach ensures that less common species are not missed.
Description
The Tickborne BBB Direct Detect Profile multiplex methodology addresses these challenges by combining two revolutionary technologies:
Digital PCR (dPCR) technology overcomes the limitation of standard PCR testing for low-abundance microbial pathogen DNA by partitioning the sample into approximately 26,000 blood droplets and then performing a PCR reaction on each droplet. This powerful
approach increases the sensitivity of standard PCR detection by up to 10 times.
Bartonella Proprietary Sample Enrichment: Bartonella species often evade detection by even the most sensitive test methods due to their low abundance in blood samples. Utilizing Bartonella Alpha Proteobacteria Growth Medium (BAPGM), portions of the blood sample are cultured to amplify the bacterial load, enhancing detectability. This sample enrichment step increases the bacterial load to detectable levels for dPCR testing.
MosaicDX offers nine (9) individual tests and combinations of the most common Lyme and co-infections in North America, with options designed to meet every practitioner’s need.
MosaicDX offers patient-friendly sample collection kits that make testing simple. Each kit includes:
- Visual, step-by-step instructions for test preparation and sample collection.
- Personalized shipping cards.
- Pediatric collection bags if needed.
Please Carefully Note Before Placing Your Lab Order
- All lab test sales are final. Once an order is placed, refunds, cancellations, exchanges, and chargebacks are not permitted, except where required by law.
- Cellular Advisory does not participate in, bill, accept assignment from, or coordinate with private insurance plans. We do not provide superbills and are unable to assist with insurance claims, reimbursement requests, or claim resolution related to laboratory testing, consultations, or related services.
- Lab kits cannot be shipped to P.O. boxes. Please provide a valid residential or business shipping address at checkout.
- After your lab test order is placed, you are responsible for carefully reviewing all instructions, completing any required sample collection or lab draw, and returning the specimen according to the laboratory’s requirements.
- All laboratory testing is performed by independent third-party laboratories, including but not limited to Mosaic Diagnostics and ZRT Laboratory, when applicable. Cellular Advisory does not operate these laboratories and is not responsible for laboratory processing times, rejected samples, delayed shipments, incomplete submissions, or laboratory-specific requirements.
- After your order is completed, you will receive follow-up instructions by email or through the applicable lab portal. Please review those instructions carefully before beginning your test.
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