MucosaGenic

• Tauroursodeoxycholic Acid (TUDCA), a derivative of bile acid produced by gut bacteria, supports fat digestion, gut detoxification, and liver function. It fortifies the intestinal and mucosal lining by protecting cells from degradation, facilitating the transport of beneficial molecules into cells, aiding in debris clearance, and enhancing the expression of tight-junction genes. Furthermore, TUDCA plays a significant role in promoting microbiome diversity, and it has also been shown to support brain and eye health, making it a comprehensive ingredient for promoting overall gastrointestinal wellness and beyond.
• Zinc L-carnosine aids in the repair of gastrointestinal ulcers and the restoration of compromised gut barriers through genetic regulation and suppression of pro-inflammatory cytokines, including interleukin (IL)-6, IL-8, and tumor necrosis factor (TNF)-α, demonstrating its multifaceted impact on maintaining intestinal health. Additionally, it reduces mucosal mRNA expression associated with cytokines like IL-1β, IL-2, and interferon (IFN)-γ, contributing to the repair of damaged gut barriers caused by chronic inflammation.
• Genistein, a potent phytonutrient, exerts its protective effects by influencing the expression and function of tight junction proteins essential for maintaining the integrity of the gut barrier. Genistein offers support for gastrointestinal health by fortifying these tight junctions, thereby helping reduce the permeability of the intestinal lining and preventing the leakage of harmful substances into the bloodstream. Moreover, its powerful anti-inflammatory properties play a vital role in alleviating gastrointestinal issues commonly associated with aging, making it a valuable component in promoting overall intestinal and mucosal health.
• L-Alanyl-L-Glutamine is essential for maintaining intestinal integrity as it regulates the expression of tight junction proteins like claudin-1, pivotal for barrier function. By promoting the development of the intestinal epithelium and finely tuning the expression of tight junction proteins, it aids in the healing process of the intestinal mucosa as well. Furthermore, L-Alanyl-L-Glutamine preserves intestinal immunity, shields against oxidative stress, and mitigates damage induced by allergens, thereby actively participating in the repair and maintenance of the intestinal and mucosal lining.
• Calcium Butyrate, a unique combination of calcium and butyrate, plays a crucial role in repairing and maintaining the intestinal mucosal lining. Calcium is essential for the proper function of tight junction proteins, ensuring the integrity of the intestinal barrier, while also stimulating the production of occludin and ZO-1 through the secretion of the gastrointestinal hormone, glucagon-like peptide 2 (GLP-2). On the other hand, butyrate, a short-chain fatty acid, supports digestion and promotes the health and healing of intestinal cells. By increasing the production of mucin 2 (MUC2), butyrate strengthens the gut barrier by forming a protective mucin layer, offering defense against harmful substances and contributing to the prevention and repair of leaky gut symptoms.

Essential Ingredients

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